Best Upsets (2021)
Rankings / Best Games (Season - Yesterday - Three Days) / Best Upsets (Season - Yesterday - Three Days) / Best Upcoming Games (Season - Today - Three Days)
Lacrosse / MCLA
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | South Carolina | #21 | 14 - 8 | #5 | Clemson | 04/09/2021 |
| 2 | Grand Canyon | #22 | 18 - 15 | #7 | Concordia-Irvine | 03/20/2021 |
| 3 | NC State | #23 | 16 - 13 | #8 | Virginia Tech | 03/20/2021 |
| 4 | Texas A&M | #26 | 9 - 8 | #12 | LSU | 04/10/2021 |
| 5 | Grand Canyon | #22 | 12 - 11 | #9 | Utah Valley | 03/06/2021 |
| 6 | Florida | #25 | 6 - 0 | #12 | LSU | 04/17/2021 |
| 7 | Massachusetts Maritime Academy | #28 | 17 - 10 | #20 | Rhode Island | 04/17/2021 |
| 8 | Arizona | #29 | 10 - 9 | #22 | Grand Canyon | 03/13/2021 |
| 9 | Oregon | #24 | 16 - 11 | #18 | Dominican | 04/10/2021 |
| 10 | NC State | #23 | 15 - 9 | #17 | Tennessee | 04/10/2021 |
| 11 | Florida State | #31 | 11 - 5 | #25 | Florida | 05/01/2021 |
| 12 | Dominican | #18 | 12 - 8 | #13 | Boise State | 03/09/2021 |
| 13 | North Dakota State | #16 | 9 - 7 | #11 | Montana | 05/08/2021 |
| 14 | St. Thomas | #14 | 13 - 6 | #10 | Missouri State | 05/08/2021 |
| 15 | Utah Valley | #9 | 18 - 14 | #6 | Minnesota | 03/05/2021 |
| 16 | Virginia Tech | #8 | 15 - 7 | #5 | Clemson | 04/23/2021 |
| 17 | Boise State | #13 | 15 - 14 | #11 | Montana | 03/14/2021 |
| 18 | Tennessee | #17 | 11 - 8 | #15 | Indiana | 03/26/2021 |
| 19 | Virginia Tech | #8 | 17 - 14 | #6 | Minnesota | 04/16/2021 |
| 20 | Chapman | #2 | 6 - 5 | #1 | Brigham Young | 04/12/2021 |
| 21 | Clemson | #5 | 13 - 10 | #4 | Liberty | 04/17/2021 |