Best Upsets (2021)
Rankings / Best Games (Season - Yesterday - Three Days) / Best Upsets (Season - Yesterday - Three Days) / Best Upcoming Games (Season - Today - Three Days)
Lacrosse / NAIA Women
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Brenau (Ga.) | #38 | 10 - 9 | #19 | Montreat (N.C.) | 03/06/2021 |
| 2 | Midland (Neb.) | #47 | 11 - 10 | #31 | William Penn (Iowa) | 04/10/2021 |
| 3 | Quincy University | #22 | 16 - 10 | #10 | Missouri Baptist | 03/03/2021 |
| 4 | Marian (Ind.) | #28 | 14 - 13 | #16 | Asbury (Ky.) | 03/24/2021 |
| 5 | Marian (Ind.) | #28 | 17 - 12 | #20 | Bethel (Ind.) | 03/03/2021 |
| 6 | Rockhurst University | #17 | 16 - 9 | #11 | Benedictine (Kan.) | 02/23/2021 |
| 7 | Point (Ga.) | #27 | 11 - 10 | #21 | Truett McConnell (Ga.) | 04/02/2021 |
| 8 | Midland (Neb.) | #47 | 15 - 7 | #43 | University of Dallas | 03/06/2021 |
| 9 | Anderson University | #24 | 17 - 10 | #20 | Bethel (Ind.) | 03/16/2021 |
| 10 | Siena Heights (Mich.) | #8 | 16 - 11 | #4 | Concordia (Mich.) | 04/20/2021 |
| 11 | Brenau (Ga.) | #38 | 17 - 16 | #35 | Huntingdon College | 02/27/2021 |
| 12 | Culver-Stockton (Mo.) | #49 | 12 - 11 | #46 | Clarke (Iowa) | 03/19/2021 |
| 13 | Marian (Ind.) | #28 | 17 - 6 | #25 | Thomas More (Ky.) | 04/07/2021 |
| 14 | Tennessee Wesleyan | #41 | 10 - 7 | #38 | Brenau (Ga.) | 04/06/2021 |
| 15 | Benedictine (Kan.) | #11 | 19 - 2 | #10 | Missouri Baptist | 04/10/2021 |
| 16 | Benedictine (Kan.) | #11 | 23 - 3 | #10 | Missouri Baptist | 04/24/2021 |